Impurity Isolation and characterization

Impurity Isolation and characterization

  • Purification of impurities from API’s, Formulations, Process samples from mg to gm scale. Specialist in isolating the impurities to 99% which are present as low as 0.1% in starting samples/Formulations.
     
  • Purification of API's From gm to kg scale.
     
  • Purification of chiral isomers from mg to gm scale.
     
  • Natural products isolation from plants, soil isolates, marine organisms etc.
     
  • Structure elucidation by NMR spectroscopic techniques using 1D like 1H, 13C, DEPT, APT, 19F, 15N experiments & 2D experiments like COSY, HSQC, HMBC, NOESY, ROESY, TOCSY, etc.

List of APIs from which we have isolated unknown impurities

These are some of the examples of APIs from which we have isolated unknown impurities. This list is not exclusive and with our experience we can work on any other API which client is interested.

No. API's
1 Tacrolimus
2 Hydrocortisone valorate
3 Esmolol
4 Methoxydienone
5 Phytonadione
6 Nifedipine
7 Osaltamivir
8 Silodosin
9 Darunavir
10 Candesartan
11 Tremadol
12 Azithromycine
13 Ertapenem
14 Miconazole
15 Rivaroxaban
16 Gabapentine
17 MethoxydienoneBivalirudin
18 Lutein
19 Ethinyl Estradiol
20 Olanzapine
21 Methyl Prednisolone
22 DLV- 8
23 Gabapentin
24 Dapagliflozin
25 Diltiazem
26 Diclofenac
27 Amphotericin –B
28 Ibuprofen
29 Trazodone
30 Vernicline
No. API's
31 famotidine
32 Triamcenolone
33 Monteleukast
34 Nebivolol
35 Pantoprazole
36 Pimecrolimus
37 Spiramycins
38 Valganciclovir
39 Flurbiprofen
40 Olopatadine
41 Dorzolamide
42 Miconazole
43 Salmeterol
44 Citalopram
45 Dexlansoprazole
46 Topiroxostat
47 Dehydroestrol
48 Vildagliptin
49 Pioglitazone
50 Nebivolol
51 Bibrocathol
52 Primaquine
53 Hydroxychloroquine
54 Tofacitinib
55 Etodolac
56 Ivabradine
57 Dihydroartemisinin
58 Sitagliptin
59 Metformin
60 Mesalazine
No. API's
61 Biapenem
62 Atovaquone
63 Cefpodoxime
64 Triamcinolone
65 Oxybutynin
66 Rifabutin
67 Lisinopril
68 Erythromycin
69 Halcinonide
70 Levothyroxine
71 Ritonavir
72 Calcipotriol
73 Methotrexat
74 Piperonylbutoxide
75 Pomalidomide
76 Resperidone
77 Trazodone
78 Temocillin
79 Netalmycin
80 Ivabradine
81 Ibrutinib
82 Voriconazole
83 Fluphenazine
84 Icatibant
85 Esmoprozol
86 Sugammadex
87 Fexofenadine
88 Dexamethasone
89

Pentoprazole

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